Pharmacology 2060A/B Lecture Notes - Lecture 11: Sulbactam, Drug Interaction, Ampicillin
22 Apr 2019
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Document Summary
Drugs can interact with each other or components in our diet to produce complicated responses. Drug-drug interactions may occur whenever a patient takes two or more drugs at the same time. Drug-food interactions may occur even if a patient is only taking one drug. The risk of drug interactions increases (almost linearly) with the number of medications a patient takes. Drug interactions are especially important in the elderly. The average 65 year old takes 7 medications, significantly more than the average 20 year old (0-1 at a time = low risk of drug interactions: more drugs = increased risk for drug interactions. The most common type of drug-drug interaction are those affecting pharmacokinetics (adme) When two drug or more drugs interact there are 3 possible outcomes: Drug interactions can increase drug effects by either an increase in the therapeutic effect or an increased adverse effect. Ampicillin is an antibiotic that is rapidly inactivated by bacterial enzymes (ineffective at killing bacteria)
