Psychology 2036A/B Lecture Notes - Lecture 7: Phosphofructokinase, Glycogen, Adrenal Gland

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With less atmosphere above you, sun rays are more intense, and you will get burnt more quickly. More citrate (from krebs cycle) as more acetyl-coa is produced (it is accumulating --> more citrate) More citrate --> will inhibit pfk in cytoplasm. Inhibition pfk (slowed production speed) in glycolysis which means that fructose-6 phosphate is going to start accumulating. You"re also going to see an inhibition of glucose being broken down. Slowing of glycolysis early and well as later in glycolytic pathways. Once glucose or glycogen is inhibited, you will fatigue. Slows down the pathway as the same rate from beginning until end. As exercise intensity gradually increases, increased hormonal stimulation activates ffa(fatty acid metabolism) (and cho) use. At higher exercise intensities lactate production starts to inhibit lipid mobilization at the triglyceride lipase step (release of fats from periphery) Atp requirement is increasing faster than the atp can be regenerated from the breakdown of fat (beta- oxidation)

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