Psychology 3316F/G Lecture Notes - Lecture 16: Genome-Wide Association Study, Tandem Repeat, Panic Disorder
29 Dec 2017
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Document Summary
Heritability of combat exposure in vietnam-era veterans ranged from. 35% to 47% (the likelihood that they are going to enroll is hetible, and the degree to which they are contributing). In civilians, exposure to interpersonal traumatic events was modestly heritable (~20%). The rge for trauma exposure appears to be explained largely by genetic influences on personality, for example, sensation seeking: relation between gene and environment by trauma exposure is mediated by personality factors. Most studies to date are hypothesis-driven: 2 types of dna sequence variation, snps (single nucleotide polymorphism or snips ): single infrequent variation in a, Dopaminergic, serotonergic, and hpa-axis molecular genetics of ptsd: Dopaminergic system (i. e. , drd2, drd3, drd4, dat1); 14 studies showing inconsistent results possibly relating to bdnf and comorbidity with substance abuse. 2009); results may also be specific to various ethnicities (e. g. , european americans but not african americans) and women vs. men.
