BI110 Lecture Notes - Lecture 8: Cholesterol, Hydrophile, Glycolipid
Document Summary
Cells and organelles need barrier to separate internal external contents. Integral membrane proteins are amphipathic, containing both hydrophobic and. Integral membrane proteins are amphipathic, containing both hydrophobic and hydrophilic amino acids. Hydrophobic domains in the trans-membrane region of an integral membrane protein stabilize it within the lipid bilayer. Integral membrane proteins contains both hydrophobic and hydrophilic amino acids. Hydrophobic domains from the transmembrane region(s) of integral membrane proteins, and stabilize them in the membrane. Fluidity of lipid bilayer is dependent on how densely individual phospholipid molecules can pack together. Effect of unsaturated fatty acids on packing of membrane lipids. Each carbon is bound to max number of hydrogens( all single bonds between c"s. If temperature drops low enough, phospholipid molecules become closely packed, and membrane forms highly viscous semisolid gel (i. e. less fluid) At low temps --> enzymes and proteins cannot function if fluidity is not maintained. At high temps --> too fluid, et leakage.
