BI110 Lecture Notes - Lecture 10: Peptide Bond, Hydrogen Bond, Alpha Helix

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12 Dec 2017
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Proteins: proteins provide structure and carry out man essential activities in the cell. Amino acid structure: amino group, r group, carboxyl group, all attached to a central carbon, shape that is created determines function. Interact with each other or with water via hydrogen bonding: tend to be on the outside of folded proteins, all polar molecules, basic amino acids are positive, even more polar, acidic amino acids are negative, even more polar. Special amino acids: glycine, proline and cysteine. Primary structure: forms strings of amino acids, peptide bond occurs between carboxyl group and amino group, ala-met-ala-met, alanine-methionine-alanine-methionine. Tertiary structure: determined by the r groups, determines hydrophobic and hydrophilic, structure according r group. Protein structure = function: functions include, structural support, membrane channels, enzymes, signalling, denatured (unfolded) proteins lose their function, some can be refolded under optimal conditions and regain function.

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