BI110 Lecture Notes - Lecture 28: Macrophage, Phagolysosome, Phagosome

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coralfish909

21 Dec 2015

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Largest molecules transported by passive and active transport are the size of amino acids or glucose. Exocytosis and endocytosis (phagocytosis: move larger molecules and particles into and out of the cell. Substances are shuttled into, out of, and within a cell through vesicles. In exocytosis, substances are directed out of a cell to be secreted by fusing a vesicle to the cell membrane. In endocytosis, substances are engulfed into a cell by the formation of a vesicle around them. Vesicle membrane fuses with pm, releasing contents to cell. Proteins in vesicle membrane become part of pm. Exocytosis at a synapse membrane: vesicles containing neurotransmitter arrive at the cell, ca2+ ion triggers the fusion of the vesicle to the, the neurotransmitter is released out of the cell membrane. Encloses materials outside cell in plasma membrane: pockets inward and forms endocytic vesicle on cytoplasmic side. Two main forms: bulk phase (pinocytosis, receptor-mediated endocytosis. Molecules bind to receptor proteins on outer cell surface.

Related Questions

I have this questions for my homework i need help with them look please it is important i need help so please give me the correct answers for each question and also please be clear to understand and aslo be correct it is very important becuase i need them so i really need the right answers. please help me and on Questions 6 and 9 please help me with it hope you can help me with the correct answers please

Question 5

At a constant temperature, if you increase the number of unsaturated fatty acid chains in the phospholipid, the membrane will become......

less fluid

more fluid

fluidity will be unchanged

Question 6

Bacteria in a hot spring at 80 degrees celsius would be expected to have ______________ in their cell membrane

high proportions of saturated phospholipids

high proportions of unsaturated phospholipids

an equal ratio of saturated to unsaturated phospholipid

Question 7

Membrane proteins have an important role in membrane fluidity

True

False

Question 8

The HIV virus can't attach to cells that have a mutation in the CCR5 gene and so such individuals are resistant to HIV. What population of people have a higher incidence of the mutant CCR5 gene and why?

europeans because their ancestors survived the bubonic plague

North Americans because their ancestors survived small pox

europeans because they have a longer evolutionary past with HIV

Africans because they have a longer evolutionary past with HIV

Question 9

Nematode trapping fungi have ______________ molecules called ______________ that recognize specific carbohydrates on the surface of the nematode worms. This is how a fungus can recognize that its prey, the nematode worm, has wriggled into the loop. Write two words on lowercase separated by a space with no other syntax

Question 10

Diffusion requires energy

True

False

Question 11

The net direction of molecule movement when molecules diffuse is

down their concentration gradient

random directions

Question 12

In osmosis, water molecules from a solution of higher solute concentration cross a semi-permeable membrane into a solution of lower solute concentration?

True

False

Question 13

Which best defines osmosis?

In osmosis, water from a solution of lower solute concentration move across a semi-permeable membrane into a solution of higher solute concentration?

In osmosis, water from a solution of higher solute concentration move across a semi-permeable membrane into a solution of lower solute concentration?

Question 14

Animal cells placed into a hypotonic solution would most likely?

lyse (burst)

shrink

remain unchanged in size

Question 15

Glucose and amino acids move into cells via carrier proteins, the same protein can move glucose or amino acids

True

False

Question 16

ATP powered pumps move substances into and out of cells by diffusion?

True

False

Question 17

For every 3 Na ions moved out, 2 K ions are moved into a cell by one cycle of the sodium-potassium pump.

True

False

Question 18

Bulk transport of fluid and any of the substances within that fluid is called

pinocytosis

phagocytosis

receptor-mediated endocytosis

exocytosis

Question 5

At a constant temperature, if you increase the number of unsaturated fatty acid chains in the phospholipid, the membrane will become......

less fluid

more fluid

fluidity will be unchanged

Question 6

Bacteria in a hot spring at 80 degrees celsius would be expected to have ______________ in their cell membrane

high proportions of saturated phospholipids

high proportions of unsaturated phospholipids

an equal ratio of saturated to unsaturated phospholipid

Question 7

Membrane proteins have an important role in membrane fluidity

True

False

Question 8

europeans because their ancestors survived the bubonic plague

North Americans because their ancestors survived small pox

europeans because they have a longer evolutionary past with HIV

Africans because they have a longer evolutionary past with HIV

Question 9

Question 10

Diffusion requires energy

True

False

Question 11

The net direction of molecule movement when molecules diffuse is

down their concentration gradient

random directions

Question 12

In osmosis, water molecules from a solution of higher solute concentration cross a semi-permeable membrane into a solution of lower solute concentration?

True

False

Question 13

Which best defines osmosis?

In osmosis, water from a solution of lower solute concentration move across a semi-permeable membrane into a solution of higher solute concentration?

In osmosis, water from a solution of higher solute concentration move across a semi-permeable membrane into a solution of lower solute concentration?

Question 14

Animal cells placed into a hypotonic solution would most likely?

lyse (burst)

shrink

remain unchanged in size

Question 15

Glucose and amino acids move into cells via carrier proteins, the same protein can move glucose or amino acids

True

False

Question 16

ATP powered pumps move substances into and out of cells by diffusion?

True

False

Question 17

For every 3 Na ions moved out, 2 K ions are moved into a cell by one cycle of the sodium-potassium pump.

True

False

Question 18

Bulk transport of fluid and any of the substances within that fluid is called

pinocytosis

phagocytosis

receptor-mediated endocytosis

exocytosis

The vesicles that transport materials from donor membranes to acceptor membranes include:

	1.	COP-II coated vesicles
	2.	COP-III coated vesicles
	3.	COP-I coated vesicles
	4.	Clathrin coated vesicles

2.5 points

QUESTION 11

During skeletal muscle contraction, the roles of ATP include:

	1.	ATP is not required for forming the crossbridges between myosin and actin filaments.
	2.	ATP is utilized as a structural linker to mediate the interaction between myosin and actin filaments
	3.	Hydrolysis of ATP provides energy for myosin head to move along actin filaments and the binding of ATP to myosin head allows the detachment of myosin fromactin filaments.
	4.	ATP binds to actin filaments to drive the power stroke of myosin head.

2.5 points

QUESTION 12

One of the functions of smooth endoplasmic reticulum is

	1.	Synthesizing steroid hormone in the endocrine cells of the gonad and adrenal cortex
	2.	Serves as the starting point of the biosynthetic pathway
	3.	Synthesizing secretory proteins
	4.	Degrading cell debris

2.5 points

QUESTION 13

The function of COP-II coated vesicles is mainly:

	1.	Transporting materials from endosomes to Golgi complex
	2.	Moving materials from the ER to the ERGIC and Golgi complex.
	3.	Transporting materials from Golgi complex back to endoplasmic reticulum.
	4.	Involved in receptor-mediated endocytosis.

2.5 points

QUESTION 14

Which of the following processes is completed in rough endoplasmic reticulum?

	1.	Chaperones help misfolded proteins fold correctly.
	2.	Proteins that target to nucleus are synthesized in rough endoplasmic reticulum.
	3.	O-linked glycosylation occurs in rough endoplasmic reticulum.
	4.	Misfolded proteins are destructed in rough endoplamic reticulum.

2.5 points

QUESTION 15

Kinesin is the motor protein that coorporates with microtubules. It has the following functions:

	1.	It uses GTP as energy source.
	2.	It can hydrolyze ATP and use the energy to drive cargo along microtubules from minus end to plus end.
	3.	It has a globular head that can act as GTPase
	4.	The tail of kinesin is more diverse and binds to cargo

2.5 points

QUESTION 16

For correct segregation and trafficking, lysosomal proteins are tagged in the cis-Golgi with phosphorylated mannose residues, and then the tagged lysosomal enzymes are recruited to clathrin coated vesicles by mannose 6-phosphate receptors.

True

False

2.5 points

QUESTION 17

The process that specialized cells, such macrophages, engulf relatively large particles is:

	1.	Called pinocytosis
	2.	Called phagocytosis
	3.	Mediated by COP-II coated vesicles
	4.	Called autophagy

2.5 points

QUESTION 18

Proteins synthesized on rough endoplasmic reticulum and smooth endoplasmic reticulum are imported co-translationally to their destinations

True

False

2.5 points

QUESTION 19

Treatment of cells with a drug that promotes microtubule disassembly disperses Golgi complex into separate stacks of membrane compartments, suggesting that:

	1.	Golgi complex is made of microtubules.
	2.	Microtubules are important for the organization of Golgi complex.
	3.	Microtubules are transported into Golgi complex
	4.	Golgi complex is composed of tubulin proteins

2.5 points

QUESTION 20

Which of the following is correct about signal sequence of a secretory protein?

	1.	It is an âaddress codesâ for protein trafficking pathways
	2.	It is usually located at the C-terminus.
	3.	It targets the ribosome and the protein that is being synthesized to endoplasmic reticulum.
	4.	It is removed in Golgi complex.

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BI110 Lecture Notes - Lecture 28: Macrophage, Phagolysosome, Phagosome

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