BI236 Lecture Notes - Lecture 18: Aminoacyl-Trna, Non-Coding Rna, Peptidyl Transferase
Document Summary
For some genes, the rna transcript is the final product. But for many other genes, the ultimate product is protein mrnas encode instructions for the precise assembly of a. a into a polypeptide (translation) Ribosomes: carry out process of polypeptide synthesis trna molecules align with a. a in the correct order: bring a. a to ribosome/mrna complex aminoactyl-trna synthetase: enzyme that attaches a. a to appropriate trna. Mrna: molecules encode a. a sequence info protein factors: facilitate some of the steps of translation. Each subunit self-assembles from rrna and proteins: ribosome is 60% rna, 40% protein. Rna does all the work and they come together only when binding the mrna. The flexibility in codon-anticodon binding allows some unexpected base pairs to form: i = inosine (most common, ml = methylinosine, gm = methylguanosine, t = ribothymidine, d = dihydrouridine. The flexibility in codon-anticodon binding allows some unexpected base pairs to form. Explains how codons differing in 3rd position can code for same a. a.
