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Lecture 16

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Louise Dawe

Biology October 23, 2013 Peripheral Membrane Proteins - On surface of membrane - Do not interact with hydrophobic core - Associate with membrane surface through non-covalent bonds (ionic and hydrogen bonds) - Most on cytoplasmic side of membrane - Made up of mixture of polar and nonpolar amino acids Passive Membrane Transport (important cell function) - Hydrophobic nature of membranes restricts free movement of many molecules and substances essential for life - Some molecules are able to cross the membrane and some of those can cross very quickly even though it’s hydrophobic - Passive transport: Movement of a substance across a membrane without need to expend chemical energy such as ATP Passive Transport (not using ATP) and Diffusion - Passive transport driven by diffusion - Diffusion: Net movement of substance from region of higher to lower concentration - Primary mechanism of solute movement within a cell and between cellular compartments separated by a membrane - Rate of diffusion depends on the concentration difference on two sides of membrane, or concentration gradient Diffusion - Driving force is an increase in entropy - The bigger the gradient, faster the diffusion rate Passive T
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