CH202 Lecture Notes - Lecture 14: Combined Oral Contraceptive Pill, Parasympathetic Nervous System, Adrenergic Receptor
• Ch202 lecture 14
• - And thus a tell tale sign that certain drugs have been recently used
• - Sympathetic nervous system
o - Adrenergic receptors (epinephrine/adrenaline)
o - “Fight or Flight”
• - Parasympathetic nervous system
- Muscarinic acetylcholine receptors
- “Relaxation”
Other factors determining drug effects: Drug Interactions
- Additive interaction (additivity)
- 5 + 5 = 10 (barbiturate + tranquilizer)
- Hyperadditive (synergistic) interaction - 5 + 5 = 20 (barbiturate + alcohol)
- Potentiation (a special kind of synergism)
- 5 + 0 = 10 (antihistamines + narcotics)
- Antagonistic interaction
- 5 + 5 = 0 (certain antibiotics + birth control pills
How long does it take to eliminate a drug? Elimination half-life
- A drug’s elimination half life refers to
