PS268 Lecture Notes - Lecture 2: Chronic Toxicity, Pharmacovigilance, Cirrhosis

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27 Sep 2020
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Lesson 2: drugs and society and canadian drug laws. 2. 2 toxicity: major reason government intervened in drug use, toxicity: the potential harms associated w/ the drug, acute toxicity: immediate harmful effects. Ie. alcohol intoxication: death by suffocation due to brainstem paralysis: chronic toxicity: harmful effects that occur after repeated use. Ie. alcohol intoxication: cirrhosis of the liver: physiological effects of toxicity, effects on body processes essential to support life. Ie. cocaine: increase in breathing and heart rate: behavioural effects of toxicity, effects that render a person incapable of responding to their surroundings, or result in poor decision making. Intravenous administration of drugs has unique toxic effects associated w/ transmission of blood-borne diseases: 99% of students would not want to inject a drug. If drug intake stopped = symptoms appear as drug levels drop. Substance-related disorders (dsm-v: encompass 10 classes of drugs: 2. 4 crime and violence: does drug use cause crime: socially toxic effects of drugs.

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