ADMS 3502 Lecture Notes - Lecture 50: Acute Kidney Injury, Malar Rash, Renal Pelvis

• School: York University
• Department: Administrative Studies
• Course: ADMS 3502
• Professor: Cristobal Sanchez- Rodriguez

Document Summary

Polyarthralgia, malar rash (butterfly shaped pattern, specific to lupus), fatigue. Labs: anemia, creatinine = 416 mol/l, urine: protein, rbc, rbc casts. Dx: acute renal failure 2 to diffuse proliferative lupus nephritis. Presence of protein in blood is due to glomerular damage. The healthy glomerulus is involved with ultrafiltration (small compounds). In a healthy, intact glomerulus, there is no filtration of protein. In glomerular disorders (nephrotic syndrome), 1-3 g/day of protein in urine is expected. If the dysfunction is in the tubule, there should be no to mild proteinuria. 56 year old black man, told many years ago he had high blood pressure (no rx) Bp 260/140, papilloedema (swelling of blood vessels in the eye) Interpretation: malignant htn will lead to narrowing of blood vessels, limiting organ perfusion. Exam: fullness on lower abdomen, pelvic rocky hard mass. Ultrasound: marked dilatation of urinary collecting system. 2 to obstruction by local spread of cervical carcinoma.