BIOL 1000 Lecture Notes - Lecture 8: Membrane Transport Protein, Facilitated Diffusion, Chemical Polarity
Document Summary
Peripheral: cytosolic side (most on this side) or extracellular side, non-covalently attached; very weak bonds, lipid anchor; going to be inserted into membrane, associated with just the polar regions. Integral proteins: inserted right into membrane, can be partial or all the way in, embedded in membrane; move within the membrane but they cant get out of membrane (hard, amphipathic; b/c interacting with polar and non polar regions. Aquaporin"s: channel in membrane specific to water, water polar molecule; it can go through but is very slow through the membrane, facilitated diffusion, use aquaporin to help speed up water going through membrane, quaternary structure. Simple diffusion: going through membrane; looking at gases no channel going. Gated more control channels aren"t always open sometimes in closed; becomes straight through. Facilitated diffusion: increasing and decreasing [] but have channels involved open when ligand is bind to it (receptor area) when it binds it changes conformational.
