BIOL 1000 Lecture Notes - Lecture 9: Mendelian Inheritance, X-Inactivation, Barr Body

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Alleles of genes that govern two different characters segregate independently during formation of gametes (principle of independent assortment) This is due to independent assortment during meiosis. More than 3 alleles for a gene. Found among all individuals in a population. Small differences in dna sequences result in multiple alleles. Dominant alleles do not completely mask recessive alleles (recessive is still seen) Allele of one locus inhibits or masks effects of allele at a different locus. Some expected phenotypes do not appear among offspring. Many different genes contribute to the same character (ex. One gene affects more than one character. Recessive allele affects hemoglobin structure and function. Damages many tissues, organs, and functions, and many different symptoms result. In female mammals, inactivation of one x chromosome makes the dosage of x-linked genes the same as males. X is random in each cell of the embryo (ex. Tightly coiled condensed x chromosome copied during mitosis but always remains inactive.

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