BIOL 1000 Lecture Notes - Lecture 5: Chromosome Segregation, Allosome, Y Chromosome

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16 May 2016

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Prokaryotic cell division and mitosis produce 2 daughter cells. Sexual reproduction produces unique offspring by union of male and female gametes (sperm and egg) Meiosis produces gametes with half the total chromosome number (46 -> 23). Mitosis, meiosis and fertilization are the stages of the animal life cycle. Animal follows mitosis, sperm/egg after meiosis and zygote after fertilization. Alleles are different versions of the same gene. Each gamete contains a different mix of alleles. Gene"s crossing over can happen anywhere along the chromosome length. It is more likely that it will happen the further apart, though. Human x chromosome is large (2350 genes) Human y chromosome is small, contains sry gene. Nondisjunction: failure of chromosome segregation at either meiosis i or meiosis ii. Euploid (normal # of chromosomes), aneuploids (extra/missing chromosomes) and. Polyploids (extra sets of all chromosomes (triploids, tetraploids etc. )) are results. Aneuploids usually prevent embryo development (down syndrome in humans is an exception)

Related Questions

Which statements pertaining to genetic variability are correct? Check all that apply (note that wrong answers will be deducted from right answers)!

Crossing over is defined by the exchange of chromosome pieces during metaphase one of meiosis.

If a germ cell (i.e. parent cell before meiosis) had only two pairs of homologous chromosomes (i.e. 4 chromosomes total) there are 2 possible combinations of maternal and paternal chromosomes in gametes.

Siblings produced by sexual reproduction are different because sperms are different from one another and eggs are different from one another, and the combination of an egg and sperm is basically unique.

Random fertilization means that all possible combinations of eggs and sperm are equally likely, i.e. it is pure chance which sperm fuses with which egg.

Individual chromosomes contain thousands of genes. This means that during each crossing over event, more than one gene is exchanged between paternal and maternal chromosomes.

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-Complete the following sentences: metaphase of mitosis, prophase II of meiosis, crossing over, anaphase I of meiosis, variable, random fertilization, identical, random orientation, metaphase I of meiosis, prophase I of meiosis, metaphase II of meiosis, reduction division

Two processes that occur during meiosis produce genetically ____________ cells.

In a process called ____________ , paired homologous chromosomes align randomly at the cell equator. This occurs during this stage of cell division: ____________ .

In a process called ____________ , genetic material is exchanged between homologous chromosomes. This occurs during this stage of cell division: ____________ .

-Complete the following paragraph to describe nondisjunction and the resulting effects on chromosome number.

words: euploidy, primary nondisjunction, nomal, nondisjunction, secondary nondisjunction, homologous chromosomes, abnormal, trisomy, monosomy, sister chromatids, aneuploid

1.During meiosis I, ____________ separate and move towards opposite ends of the poles.

2.During meiosis II, ____________ separate and move towards opposite ends of the poles.

3.During meiosis I, if both members of a homologous pair go into the same daughter cell, ____________ is said to occur and no normal gametes are produced.

4.During meiosis II, if the sister chromatids fail to separate and both daughter chromosomes go into the same gamete, ____________ is said to occur. Half the gametes are aneuploid while the other half are euploid.

5.If an egg that contains 24 chromosomes instead of 23 chromosomes is fertilized by a normal sperm, ____________ is said to have occurred.

6.If an egg that contains 22 chromosomes instead of 23 chromosomes is fertilized by a normal sperm, ____________ is said to have occurred.

Title: Meiosis Lab

Part 1: Modeling Meiosis Without Crossing Over (reformat as needed)

Take photos of the following stages of your meiosis bead simulation. Insert and label the following images:

Meiosis 1: Prophase I and Metaphase I

Meiosis 2: Metaphase II and Telophase II

Part 2: Modeling Meiosis With Crossing Over (reformat as needed)

Take photos of the following stages of your meiosis bead simulation. Insert and label the following images:

Meiosis with Crossing Over: Metaphase I and Telophase II

Questions â use the lab Introduction, your textbook and other sources to answer the following.

What is the state of DNA at the end of meiosis I? Are the chromosomes replicated or unreplicated? Diploid or haploid?

Why are chromosomes important?

How are Meiosis I and Meiosis II different?

Name two ways meiosis contribute to genetic recombination or genetic variety.

Why do you use non-sister chromatids to demonstrate crossing over? What would happen if you crossed over sister chromatids?

How many chromosomes were present in your simulation when meiosis I started?

Why is it necessary to reduce the chromosome number in gametes, but not in other cells of an organism?

If humans have 46 chromosomes in each of their body cells, determine how many chromosomes you would expect to find in the following:

Sperm	Egg	Daughter cell after mitosis	Daughter cell after meiosis

Investigate a disease that is caused by a chromosomal mutation due to nondisjunction. When does the mutation occur? What chromosome is affected? What are the consequences?

BIOL 1000 Lecture Notes - Lecture 5: Chromosome Segregation, Allosome, Y Chromosome

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