BIOL 1000 Lecture Notes - Lecture 1: Membrane Transport Protein, Glucose Transporter, Passive Transport

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The further apart lipids are from one another, the more fluid the membrane is. More saturated fatty acids = more fluidity. High temperature = unsaturated fatty acids = high fluidity. Organisms adjust fatty acid composition at different temperatures in order to maintain optimum fluidity for the function of that membrane. Cholesterol permits fluidity at even lower temperatures since packing opportunities are reduced. Small hydrophobic molecules readily diffuse through bilayer (with concentration gradient) Peripheral proteins are attached to one hydrophilic side (intra or extracellular) and are primarily found in cytosolic (intra) side. Integral proteins are inserted into the membrane and are amphipathic (interact with both polarities). Transmembrane proteins are the most common integral proteins. Cross the entire membrane (from extracellular to intracellular space). Na+ glucose transporter) are very specific with what they transfer and transfer across the membrane when everything is bound (both. Na/glucose: passive diffusion: diffusion across the membrane based on concentration gradient.

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