BIOL 1500 Lecture Notes - X-Inactivation, Sex Linkage, Y Chromosome

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Sex-linked genes: genes located on sex chromosomes, they are inherited differently in males and females. Autosome: chromosomes other than sex chromosomes, the genes have the same patterns of inheritance in both sexes. Females have two copies of the x chromosome, a fully homologous xx pair. Males have one x chromosome and one y chromosome. The y chromosome has a short region of homology with the x chromosome that allows them to pair during meiosis. When a sperm cell carrying an x chromosome fertilizes an x-bearing egg cell, the new individual develops into an xx female. When a sperm cell carrying a y chromosome fertilizes an x-bearing cell, the combination produces an xy male. Sry gene carried on the y chromosome is the master switch that directs developments toward maleness during embryonic development. After 6-8 weeks of embryonic development, the sry gene becomes active in.

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