BIOL 2060 Lecture Notes - Lecture 44: Potassium Superoxide, Respiratory Tract, Aorta

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Hypoxia, hypoxia: low partial pressure at altitude of oxygen & atm. Anemic hypo: low o2 (cid:272)o(cid:374)te(cid:374)t, (cid:271)lood loss, less h(cid:271), h(cid:271) (cid:272)a(cid:374)"t (cid:271)i(cid:374)d to o(cid:1006), less rbcs. Is(cid:272)he(cid:373)i(cid:272) hy: blood flow issue (low blood delivery, heart attack), low blood pressure. Increase ve, get rid of plasma & up hematocrit (rbcs), up rbc synthesis (slow), increase capital den- long term increases carrying capacity of o2. Asthma low flow rate, inflammation in airways, thick mucus due to exposure to allergen, irritants, infections. Copd- volume of air same, but airflow slow. Emphysema: destruction of trypsin causes breakdown of alveolar walls, collapse airways. inabiliy to produce protective antitrypsin. Anti-inflammatory drugs (orange)- glucocorticoids & leukotriene inhibitors- cause constriction, slow. Bronchodilator (blue): mimics epi to dilate & inhibit acetyl. Air equally distributed in lungs & efficient gas exchange b/c greater sa. Va= tv-dead x rr amount for gas exchange. Less amount of air exchanged with atm & alvo/ breath.

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