BIOL 2070 Lecture Notes - Lecture 1: Meta-Analysis, Moodle, Turnitin

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13 Apr 2016

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On day 1, one of four articles will be available for you to choose from on a relevant topic and your job is to summarize it in a two-page, 1. 5 spaced report. Summary report, you should provide a clear and brief introduction to the subject, a brief description of the paper"s methodology and how it was used to generate the results. You should have a thorough and focused summary of the authors" results, main findings, implications and future work. List the authors" conclusions and remark on what you think the direction of the field will be in light of the authors" findings. You are expected to have a preliminary summary report, in other words, a detailed draft, prepared for day 4. The draft will not be submitted to turnitin. Day 4 lab, you will anonymously peer-edit a classmate"s summary report and provide them with constructive criticism to aid them in writing a better report.

Related Questions

Article: Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimerâs pathology

https://bbl.westfield.ma.edu/bbcswebdav/pid-1058990-dt-content-rid-12869706_1/courses/wsu_BIOL0333001_2018fall/Alzheimers.pdf

-Please do not use direct quotes from the article-

2. Hypotheses:

a) What are the hypotheses? (list all hypotheses proposed)

b) Is the reasoning behind the hypotheses explained? What is the logic behind each hypothesis?

3. Introduction:

a) Does the introduction provide appropriate background for the study? Why or why not?

b) Is the introduction missing useful information that would have been helpful? If so, explain. For example, did you have to look up any additional information?

c) Is the relevance of the work clear? What is the relevance of the work?

4. Methods:

a) Summarize the methods that were used.

b) Were the methods appropriate? {Was this the best way to test the hypotheses? Were there problems with the methodology (if so describe them)?}

5. Analysis:

a) Were there any problems with the data analysis, including use of statistics?

b) Did the authors present quantitative data in a clear way (use of graphs/tables)?

6. Your OWN assessment of the results:

a) List YOUR conclusions from the DATA presented?

b) Do you feel that the author's conclusions are reasonable and justified? If there are any problems with the authorâs conclusions, explain them.

c) Does the author ignore any aspects of the results?

7. Discussion:

a) Did the authors compare their results with previous published papers? If so, provide at least 1 example.

b) Are the implications of the results properly discussed (how do these results relate back to the âbig pictureâ of what is being studied)? What are the implications?

c) Are the conclusions clearly stated? If so, what are they?

d) In addition to what the authors discussed, what further studies would YOU find interesting to pursue?

8. Abstract (if there is one):

a) Does the Abstract really give an appropriate summary of the paper?

write a paragraph of at least 200 words (double spaced, with 12-pt Times New Roman or similar font) about the article. These paragraphs should summarize the work presented in the paper and should be in the style of a scientific abstract. An abstract is a 1-paragraph summary or synopsis of the main points of an article. Abstracts typically begin with a statement about the problem the research addresses and then include brief descriptions of the methods used, the results/findings, and the main conclusions. Abstracts are usually between 100-500 words and are typically less than 1 page in length. The minimum length for the summaries in this course is 200 words, and the length should not exceed 1.5 pages (double spaced). In addition to summarizing the research, I would like you to add 1-3 sentences in which you evaluate the research. These evaluations may include statements about any flaws you noticed in the research, additional experiments that could or should be performed, or your own insights into the broader impacts of the research.

The article selected is : âMycobacterium tuberculosis Hip1 Modulates Macrophage Responses through Proteolysis of GroEL2â
Naffin-Olivos JL, Georgieva M, Goldfarb N, Madan-Lala R, Dong L, Bizzell E, et al. (2014) Mycobacterium tuberculosis Hip1 Modulates Macrophage Responses through Proteolysis of GroEL2. PLoS Pathog 10(5): e1004132. "

https://jeccr.biomedcentral.com/articles/10.1186/s13046-015-0130-0

This is the link to the research article

1. Describe in 3 sentences or less WHY the authors conducted this research â what was their goal? (4pts)

2. For each of the figures (1-5) provide a one sentence description of the PURPOSE of the figure AND a one sentence CONCLUSION of the experiments in the figure. (15pts) Note that: a. You only need to provide one sentence for the entire figure, not for each panel (a, b, etc.) of the figure. This requires you to summarize info from multiple panels into a concise and informative sentence. b. The purpose of the experiment is a âWhyâ not a âhowâ or âwhatâ. Your answer should not describe what the figure shows, but why the experiments were done, i.e, what was the goal of doing the relevant group of experiments. c. The conclusion is the take-home message of the figure. As immediately above, your answer should not be a description of what the figure shows, but what the researchers deduce from the experiment

3. In your view, what is the most important figure in the paper? Why? (3pts)

4. In your view, what is the next logical experiment that should be performed given the results presented in the paper? (3pts)

BIOL 2070 Lecture Notes - Lecture 1: Meta-Analysis, Moodle, Turnitin

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