BIOL 3070 Lecture 32: Lecture 32 - AP

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8 Jan 2016
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Nak also sig. reduced (imp"t for getting sodium into blood but not as critical as in seawater) As move from cortex to inner medulla, increasing osmotic gradient in cortical regions, isosmotic (300mosm), then deeper medulla can have 1200mosm. Diff cell types associated with diff parts of the nephron. Ultrafiltrate formed called primary urine in proximal tubule, has very extensive network of microvilli on apical surface since involved in reabsorption. Descending limb is very thin layer of cells; little mit. present; highly permeable to most solutes and water. Distal tubule has some functions in reabsorption as well as maintaining proper acid-base balance collecting duct has similar functions to distal tubule (both under control of various hormones like adh) Henle; they follow anatomy of loop of henle so they have ushaped type of arrangement; they"re important for maintaining osmotic gradient within inner regions of medulla. S=amount secreted (whatever solute/ions removed from blood into nephron)

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