BIOL 3155 Lecture Notes - Lecture 17: Icosahedral Symmetry, Symmetry, Capsomere
17 Feb 2018
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Document Summary
For polio, vp1 is attachment protein; the way the virus recognizes the receptor on surface of host cell. icosahedral symmetry based on the rotation known as 2-3-5 symmetry. *refer to image of the types of folds. 3 fold symmetry: will result in three equal pieces. virus uses few proteins that are used over again; thus structure has to be symmetric. 3vp2 + 3vp3 and penton: 5 vp1. penton is formed at the corner. If larger virus, can change the number of hexon capsomers and still have the same structure. pentons - must be exactly 12 (1 for each corner) hexon - 20 (one for each face) or multiple of 20. In adenovirus, each face is made of 12 hexon capsomers. Hexons made of 6 proteins but can cover larger surface by having each protein surrounded by 6 around and so on.
