BIOL 4010 Lecture Notes - Lecture 8: Pigment, Molluscum Contagiosum, Immunodeficiency
30 Dec 2020
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Ill defined: erythema and inflammation, scales, excoriations. Psoriasis: well demarcated, red scales, sausage-like presentation on skin. Acne: acne vulgaris: comedomes, papules, pustules, drug induced: inflammatory papules and pustules. Secondary: residual hyper pigmentation, excoriated papules and scars. Inflammatory reaction: p acnes feeds on sebum, prolif. If no regression, likely to progress to proliferation: genetics, hormonal changes, e. g. puberty or, children and young adults. Inflammatory skin disorder: chronic inflammation, a/w cutaneous and mucous membrane hyper- reactivity towards enviro triggers, genetics: ige mediated hypersensitivity, genetics: mutation in fillagrin, epidermal barrier protein important for barrier and moisture retention. If present: more severe, earlier onset, high level allergen sensitization, asthma development. Medications that can cause: asthma, allergic rhino-conjunctivitis, allergies, -blockers, nsaids. Athlete"s foot: occur on webs or soles of feet. Look in groin, palms, scales, toe webs, arch: pruritis, burning, redness and inflammation. Chronic (fungus: dry, flaky, scale within creases.
