KINE 1020 Lecture Notes - Lecture 9: Serotonin Receptor Agonist, Lorcaserin, Combination Drug
Document Summary
Possible physiological consequences of repeated cycles of weight loss and weight gain. Increased preference for dietary fat: decreased metabolic rate, fat pooping drug decreases the intake, you poop it out, glreotide (injectable protein) is an appetite hormone, hormone released from intestine. Increased ration of total fat to lean mass. Increased cancer risk factor goes back to brain and say i"m full . Prescription weight loss drugs: appetite and absorption, or stimulant, we have 3 weight loss pills in canada, xenical (1999) orlistat (pooping drug, saxenda (2015) liragultide (intestinal, contrave (2018) bupropion/naltrexone (combination drug of depression/smoking mixed with alcohol drug, approx. 250/month) (losing weight, losing weight drug: sibutrimine (meridia): Is an appetite control pill (most common weight loss drug in canada) Side effects: headache, nausea, dry mouth, constipation, insomnia, increased heart rate, increase blood pressure. Pulled off market in 2010 because of side effects: fen phen. Resulted in pulmonary hypertension (thickening of lungs, hard to breathe)