KINE 1020 Lecture Notes - Lecture 31: Progressive Muscular Atrophy, Calcium Atpase, Myasthenia Gravis

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The inability to maintain the required power output which is related to a decline in either force/velocity. A condition in which there is a loss in the capacity for developing force/velocity of muscle resulting from muscle activity under a demand/load which is reversible by rest. Running for 15mins then stopping is not fatigue but exhaustion as you have not lost the force output. Task limitation: stopping an activity (exertion, exhaustion, end point in some time when you stopped what you wanted to do) Not necessarily a decrease in the capacity of the muscle to produce force when you stop at exhaustion. Many sites: central peripheral: contribution of the different sites may vary based on the nature of the task/physical activity, central: supraspinal (minimal) and spinal. Motor cortex and supraspinal outputs (afferent/efferent signals) Upper/lower motor neurons: peripheral: membrane and contractile components.

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