KINE 2011 Lecture Notes - Lecture 8: Enzyme, Activation Energy, Manganese

• School: York University
• Department: Kinesiology & Health Science
• Course: KINE 2011
• Professor: Ali Abdul Sater

Document Summary

The role of enzymes in biological reactions: most reactions must occur at high rates to sustain life, factors control rate of chemical reactions. Enzyme accelerate rxn by reducing activation energy: catalyst: a chemical agent that speeds up rate of rxn w/o taking, enzymes are biological catalysts found in the body, enzymes increase rate of rxn by lowering activation energy. Lowering transition state allows more molecules to react w/adequate energy. Enzymes combine w/reactants: su(cid:271)strate: it"s a rea(cid:272)ta(cid:374)t that a(cid:374) e(cid:374)zy(cid:373)e a(cid:272)ts o(cid:374, active site: the specific site on an enzyme where substrate binds. This is where catalysis takes place: cofactor: non-protein group that binds precisely to enzymes, cofactors include metals (iron, copper, zinc or manganese, essential for catalytic activity of enzymes, cofa(cid:272)tors: type of (cid:272)ofa(cid:272)tors that"re orga(cid:374)i(cid:272) (cid:373)ole(cid:272)ules derived fro(cid:373) vitamins. Mechanisms that lower activation energy: bringing reacting molecules together, exposing reactant molecules to altered charge environments that promote, changing shape of substrate molecule.