KINE 3012 Lecture Notes - Lecture 5: Renal Corpuscle, Efferent Arteriole, Afferent Arterioles

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Nephron: smallest bit, does the work of this filtration. Renal corpuscle: where the blood comes in where you gain that filtrate. Tubule: there are about 1 million nephrons in the kidney per kidney, each one is heavily vascularized. By the time the urine is in the ureter, it is in its final composition, the bladder does not make any changes. Pathway of filtrations: filtrate has to make it through all these components and slightly different things happen to the filtrate in each step. Renal corpuscle of all nephrons is in the cortex. Loops of henle are located in the medulla, which gives them that striated appearance. Juxtamedullary nephrons have the long loops of henle, they produce most concentrated urine, make up 20% of the nephron. Corticol nephrons: some of loop is in cortex itself, does not descent as much deeper, makes up 80% of the nephron.

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