NATS 1540 Lecture Notes - Lecture 59: Beta Blocker, Ventricular Fibrillation, Digoxin
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Sotalol should never be used as a heart rate control agent. Carvedilol very favored agent in heart failure but not in a fib (not first line agent) Acebutolol any with intrinsic sympathomimetic activity (potentially makes patients more tachycardic) Rapid heart rate control: iv metoprolol, propranolol, esmolol (half life of 9 minutes, never used) Not as effective in controlling heart rate but increase exercise tolerance with. Er preparations do not use in people at the beginning (acute phase). You give it later when you find out what dose they need to be on. Worry about low heart rate when it causes symptoms if asymptomatic, it"s ok. Less effective than ccb and bb not effective in people who exercise (high sympathetic tone) Renally excreted drug interactions p-gp elimination. Too much digoxin digitoxic when they were cardioverted, a lot of them converted to ventricular fibrillation. They space the dose in 12 hours delayed onset so the effects come later .