NATS 1670 Lecture Notes - Lecture 17: The Smoking Gun, Boogie 2Nite, Chronic Obstructive Pulmonary Disease
25 Mar 2014
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Document Summary
Mutated genes can induce cancer (epidemiology of cancer) Human cancers in all cases have more mutations compared to other cells. Cancer is a result of mutations of a maybe a certain gene; it can usually be a genetic gene. 20% of cancer is transmitted from parents to kids: cancer is in essence a genetic disease. It"s caused by mutation of genes: mainly somatic non-heritable. Spontaneous-6. 4 billion cells have to be copied annually. The smoking gun: the classic mechanism of lung carcinogenesis is based on the fact that carcinogens in the tobacco end up causing dna mutations, tobacco smoke consists of approximately 60 known components that have adverse biological affects. Adler (1912): primary neoplasms of the lung are among the rarest forms of the disease . 5 year survival of lung cancer is 15% 600, 000 people are dying every year in the us due to smoking dep. iarc. fr/ 22% of canadians aged 15-19 years old, were smokers in the year 2001.
