NATS 1670 Lecture Notes - Lecture 16: Missense Mutation, Frameshift Mutation, Nonsense Mutation

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25 Mar 2014
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Is a mutation that changes one amino acid to another. A point mutation that causes a change in the amino acid sequence of the protein is a missense mutation. A point mutation that creates a new stop codon is a nonsense mutation. Cgg tct ttg atg aag frame shift mutation (insertion) Arg ser phe asp glu: frameshift mutation is a result of addition or deletion of one or two nucleotides (or multiple of them, likely to create a new triplets of nucleotides. New (useless) sequence of protein from the point of the mutation. Consequences of mutation: selective advantage: we are different from one another, one may be better in sports than others. We started as a simple organism like bacteria. Many mutations can make us do better especially in the human environment. When we are exposed to human environmental factors, our old environment. Evolution: evolution is the change in the inherited traits of a population of organisms through successive generations.

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