NATS 1670 Lecture Notes - Antigen-Presenting Cell, Autoimmune Disease, Clonal Selection

• School: York University
• Department: Natural Science
• Course: NATS 1670
• Professor: Motti Anafi

Document Summary

Specific (adaptive): effects after few days, leads to a state of immune memory, high specificity- improve during the course of respons. A response to a specific immune stimulus (antigen) The immune system can remember invaders and react more promptly to second exposures to infection. - only an exposure to the same antigen will activate this memory response. The specific immune system is normally distinguishes between self- and non-self and only reacts against non-self. Antigens (ag, antigenic determinants) - substances that induce a specific immune response and subsequently react with the products of a specific immune response. Antibodies (ab, immunoglobulins, ig) - protein molecules that are produced by plasma cells in response to an antigen and can bind specifically to that antigen. - are proteins that serve as molecular weapons of defence. Antibodies have a specific shape and are made out of regions that are very specific to the pathogen and have a region that is different from other antigens.