NATS 1670 Lecture Notes - Lecture 4: Missense Mutation, Dna Replication, Point Mutation

• School: York University
• Department: Natural Science
• Course: NATS 1670
• Professor: Motti Anafi

Document Summary

Assembled along an mrna to increase the rate of protein production. Human dna of one cell is approximately 2 meters long. In the living cell, dna undergoes frequent chemical change, especially when it is being replicated. Those that are not result in a mutation. Thus, mutation is a failure of dna repair. Mutations can result from the incorporation of incorrect bases during dna replication. Most such spontaneous changes in dna are temporary because they are immediately corrected by processes collectively called dna repair. Most damage to dna is repaired by removal of the damaged bases followed by resynthesis of the excised region. There are dna mechanisms to help repair what is damaged. Exo1 removes the damaged part of dna so a polymerase can remake that section. A mutation: is any change in an organism"s dna sequence. Proteins, encoded by the genotype, produce the phenotype.