SOCI 3630 Lecture Notes - Lecture 4: Antibiotic Prophylaxis, Cefalexin, Nitrofurantoin
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Lo 12: describe patients who are candidates for antibiotic prophylaxis for utis. Differentiate between post-coital and continuous suppressive therapy of urinary tract infections, including potential options and dosing regimens. Patients who are candidates: females who experienced two or more symptomatic utis within 6 months, females who experienced three or more symptomatic utis within 12 months. Post-coital prophylaxis: post-coital prophylaxis involves taking a single dose of antibiotic within 2 hours of sexual intercourse and it is demonstrated to be effective in reducing infection rates, and is considered as effective as continuous antibiotic regimen. It can be a more acceptable method of prevention than continuous prophylaxis in women whose utis appear to be temporally related to sexual intercourse. Involve long-term (6-12 months) antibiotic prophylaxis at a lower dose compared to treatment dose. It is only recommended for young women and not recommended for patients with neurological conditions or abnormal urinary tract: although rcts demonstrated efficacy of reducing infection rate within 6-