PHYS 215 Lecture Notes - Lecture 51: Neuropeptide Y, Leptin, Orexin
31 Dec 2018
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Lecture 21 (part 2) energy balance and temperature regulation. Important short-term control affecting food intake: gi distension suppress or dec food intake. Inc orexins stim or inc food intake (via dec in blood glucose?: other inc body temp after eating (specific dynamic action of food) suppress food intake, other compounds other neurotransmitters (dopamine, serotonin, etc. ) Influenced by drugs: psychological factors that affect food intake, stress, anxiety, depression, boredom. Inc or dec food intake: smell, taste, texture of food. Inc or dec food intake: eating patterns, availability of food. In fasting, inc ghrelin causes an inc in orexins: what is pyy 3-36, hormone made by small and large intestine, supress appetite via dec neuropeptide y. Is our metabolic rate: calogenic hormones, thyroid hormones (t-3/t-4) Inc metabolic rate: major determinant of metabolic rate, epinephrine, catecholamine. Inc metabolic rate (acute effect; thyroid hormones must be present: muscular activity inc activity = inc metabolic rate, food ingestion food inc metabolic rate (food-induced thermogenesis)
