NSC 3356 Lecture Notes - Lecture 12: Nucleus Accumbens, Limbic System, Lipophilicity
12 Mar 2017
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Alcohol: effects of alcohol on neuronal membranes, figure 10. 14. This chemical is lipophilic it does not like proteins (does not bind to proteins) it does not have a way to bind to a ligand bound receptor so instead it dissolves in the membrane. It"s a small molecule making it a true organic solvent. If enough is present it can alter g-proteins. It changes the way especially peptides do maintenance. Not everyone is good is at this they are impulsive even though they know the rules. If they do not have this kind of inhibition we call them sociopaths: they do not act out of fear. In sum this is an important because it is most sensitive and alcohol facilitates the movement of cl to make you less anxious. Cutaneous dilation: lose body heat fast, which is why its used as a solvent in cough meds. Anxiety relief: but the best way is psychotherapy.
