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Immune System and Hemodynamics Notes.docx

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Department
Communication
Course
COMM 1020
Professor
Dibenedetto
Semester
Fall

Description
Immune System • Innate immunity (nonspecific) – phagocytes, macrophages, NK cells, neutrophils o Antigen independent, immediate, no immunologic memory • Adaptive immunity (Humoral) – lymphocytes (T and B cells) o Antigen dependent, lag time between exposure and response,  immunologic memory • Inflammation o Inflammation mediators released – histamine/complement o Chemotaxis, increased blood flow, increased vascular permeablility o Increased leukocytes at tissue o Bacteria destroyed • Fever Production o Increased blood flow to tissue causing increased temperature, redness,  swelling, and pain Hemodynamics • Blood vessel anatomy o Tunica interna – w/ endothelium, loos connect tiss o Tunica media – smooth muscle, blood pressure o Tunica externa – collagen fibers protect o Artery vs Vein  Arteries have more smooth muscle and elastic fibers  Veins have a greater diameter o Capillary types o Metarteriole – precapillary sphincters  Continuous – skeletal muscle, lungs  Fenestrated (pors)– Kidneys, brain  Sinusoid (incomplete basomembrane) ­ liver o Flow = a volume, rate of flow = 1/resistance   Main effector is vessel radius  Laminar vs
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