PSYC1110 Lecture Notes - Lecture 12: Tegmentum, Pseudorandom Binary Sequence, Blood Alcohol Content

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Tolerance decreased sensitivity to a drug as a consequence of exposure to it. Tolerance - decreased sensitivity to a drug as a consequence of exposure to it. Shift in the does-response cure to right. In the end you need to take more amount to achieve to the same effects. Can take with other drugs that aren"t meant to get high. The primary drug to parkinson ,supplant diminishing dopamine by giving pools of dopamine: but over the course of five or ten years, you have to increase the doses due to the tolerance. Metabolic less drug is getting to the site of action. Functional decreased responsiveness at the site of action; Cross tolerance exposure to one drug can produce tolerance to similar drugs. E. g: alcohol and benzodiazepines(treat anxiety disorder: both work on the gaba receptors, if drink a lot, over stimulating the receptors, the number of the receptors are going to reduce, and thus needing more doses of benzodiazepines.

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