BIOL-242 Lecture Notes - Lecture 28: C3B, Macrophage, Phagocytosis
20 May 2020
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Chapter 21 part 9 | the immune system review. Much easier for the macrophage to bind to the c3b on the bacterium, and easily engulf it for phagocytosis. The bacterium will also have fc on it, and the macrophage has fc receptors. In the plasmatic membrane, complements assemble together to form a pore (hole) in the membrane, causing the lysis of the cells. T h 1 - helping macrophages (they can produce bleach in their vacuoles to kill bacteria and viruses. T h 2 - helping b cells to make antibodies. The cytokines are one of the signals / requirements for a t cell to activate. When the tlrs are activated; when the macrophages bind to pathogen, the. Naive t cells absolutely need a tcr (not to be confused with tlr) that eventually binds to a foreign antigen on the macrophage. Cd4 molecule that eventually binds to mhc class ii (mhc is binded to the antigen already)
