BIOL 311 Lecture Notes - Lecture 8: Foreskin, Extracorporeal, Endothelium
20 Sep 2016
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We can work w/ a single cell type in isolation. Recombinant dna technology biologics (began in 1982 w humilin) gene function. Tissue engineering - ability to make artificial tissue. Basic research - ie understanding the function of cells. Artificial environment therefore, may not be in vivo life. Cells can change their genotype hela cells mabs - hybridomes. Challenging to express the proper phenotype (physical appearance of organism) ie mdck cells + caco-2 (kidney) {see diagram} Not all cells can be grown in culture. Function can be lost creases with time, while their viability remains the same) lets talk about hypatosytes (they do not divide, just sit there there function de- Growth media, 3: cell line vs. cell strain. Cell strain has a finite number of doublings hayflick hypothesis - number of cells in cell culture is indirectly related to age (if i heard that right)
