CAS BI 315 Lecture Notes - Lecture 12: Thyroid, Adrenal Gland, Adrenal Medulla
15 Jan 2017
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*read section on the adrenal glands, cortisol, and regulation of stress* Hormones: reproduction, growth, differentiation, blood pressure, behavior, mood, mineral balance (calcium, potassium and sodium), appetite, digestion, fight/flight, nervous system response, body temperature, water balance, etc. 11. 4) o derived from cholesterol cholesterol serves as the backbone of enzymes: estradiol (in the ovaries/estrogens), testosterone (testes/androgens), cortisol, progesterone, aldosterone. Cortisol (often used to treat skin hydrocortisone) Predhistone (cortisol agonist): coritsol derivative: cortisol mimic; has a longer half-life in the blood; not removed from circulation; very powerful. *estradiol (one estrogen); 3 different estrogens in women. 1,25-dihydroxycholecalciforol = vitamin d after 2 hydroxilations in the liver and kidneys. When the vitamin d is hydroxylated, it gets secreted into the blood, travels through the circulation and acts on a distant target ex: bone or intestine. **vitamin d is not a hormone it is a ligand; must be activated by the body to become a hormone 1,25-dihydro .
