CAS BI 385 Lecture Notes - Lecture 2: Senescence, Neutrophil, White Pulp

• School: Boston University
• Department: Biology
• Course: CAS BI 385
• Professor: Trevor Siggers

Document Summary

Chapter 1 continued: elements of the immune system and their roles in defense. 10. importance: flux of lymphocytes allows for surveillance of pathogens in secondary lymphoid tissue. 12. lymphocytes meet pathogens in lymph nodes: activation of lymphocytes. 13. tiny fraction of t and b cells with receptors that bind the pathogen will be activated: activated t cells leave to go to tissue and kill pathogens, activated b cells will become antibody producing plasma cells. 14. activation of adaptive immunity response in a draining lymph node: increase in size of lymph node as a result of proliferation of activated lymphocytes (swollen glands, spleen. 15. lymph node for blood-borne pathogens, filters blood: removes deamaged of senescent (old) red blood cells, acts as secondary lymph organ against blood-borne pathogens. 16. dendritic cells, macrophages take up pathogens in blood, stimulate b and. 17. organization and function of splenic white pulp similar to the lymph nodes: secondary lymphoid tissue of mucosal surfaces. 18. respiratory and gastrointestinal tracts contain many secondary lymphoid organs.