BIO 105 Lecture Notes - Lecture 10: Contact Inhibition, Biopsy, Telomerase
Document Summary
Check to make sure there are enough nutrients. Can be sent to death if it cant be fixed. Make sure the spindle fibers are correctly attached. Photo-oncogenes: normal genes growth factor or receptor. Oncogene: abnormal protein, or too much (an increase in cell division) The oncogene doesn"t need a growth factor it will signal the cell to divide in the absence of a growth factor. Normal protein becomes an abnormal protein because of a mutation no longer performs its job. Progression from benign tumor to cancer requires many mutations. Angiogenesis: redirect the blood vessel to the tumor at the expense of the normal cells. Loss of contact inhibition: division stops after the surface is filled. Cancer cells don"t care and they lose contact inhibition and keep growing. Loss of anchorage dependence: normal cells need to be anchored to a surface or another cell but cancer cells don"t care. Biopsy: surgical removal of cells or fluid for analysis.
