BIOL-4610 Lecture Notes - Lecture 16: Endoplasmic Reticulum, Lipid Bilayer, Flippase

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Send lipids and proteins to golgi apparatus for modification. Transitional elements: role in formation of transition vesicles. Shuttle lipids and proteins from er to golgi aparatus. Concentration of both depends on cell function. Glycoproteins embedded in plasma membrane and help signal to other cells what the cell is. Liver cells have a bunch of this. Sarcoplasmic reticulum = example of smooth er specialized in calcium storage. Phospholipids are incorporated into the membrane via vesicles. Flippase: takes phospholipids and flips them to the lumenal side of the bilayer. Phospholipid exchange proteins: convoy specific phospholipids to specific organelles. The half life of mrna is very important in determining how many copies of protein can be made. Cytosolic free ribosomes: not bound to the membrane or does not bind to er membrane. The protein has no signal once translated not being fed into the er membrane so it doesn"t need a key to get in.

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