BIOL-4670 Lecture Notes - Lecture 3: Hydroxycarbamide, Monomer, Benzene
Document Summary
Increased amount of polychromatophilic red cells on wright stained blood smear will be seen. Indicates marrow response following actue blood loss or. Intact marrow function, sufficient epo, and nutrients for hgb synthesis and cell division: normal rbc survival depends on maintaining rbc membrane/shape and. Anemia: decreased rbc count, hgb or hct values compared to normal reference range. True anemia decreased rbc mass and normal plasma volume: pseudo/dilutional anemia normal rbc mass and increased plasma volume, pregnancy, volume overload, congestive heart failure, tissue hypoxia, many causes sign of deficiency of disease, hematological response. Increased renal release of epo to accelerate bone marrow erythropoiesis. 2: normal bone marrow can increase its activity 7-8x normal rate, becomes hypercelluar, m:e ratio decreases, nucleated rbcs sometimes released with retics. High n-rbcs is correlated with severity of anemia. If demand exceeds maximal activity extramedullary production begins: signs of accelerated bone marrow activity polychromasia and.
