NUTR-4550 Lecture Notes - Lecture 2: Gluconeogenesis, Insulin, Crtc2
Document Summary
Slide 1: how fuel is used and released aka how it gets energy and what energy products it forms (figure 19. 1) Brain: uses glucose and ketone bodies, it rarely uses lactate (would be made in the cory cycle) Intestine: uses glucose and glutamine, releases lactate and alanine. Skeletal muscle: uses glucose, free fatty acids, triacylglycerides, and branch-chained amino acids, releases lactate, alanine, and glutamine to the liver. Heart: can only utilize fuel and doesn"t release anything. Its a highly aerobic environment so it favors fatty fuel sources: uses free fatty acids, triacylglycerides, ketone bodies, glucose, and lactate. Liver: uses amino acids, free fatty acids, lactate, glycerol, glucose, and alcohol. It prefers to use amino acids and fatty acids: releases glucose, ketone bodies, lactate, and triacylglycerides (tags) The tags could from chylomicron development or by consuming excess fat. Saturday, january 27, 2018: use glucose, free fatty acids, ketone bodies, lactate, and glutamine, release glucose when renal gluconeogenesis is happening.
