BMS 420 Lecture Notes - Retina, Perfusion, Pulmonary Artery

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3 Apr 2014
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Only about 1% are affected by growth factors to do so. Flux: amount of solute moving across capillary wall/time. Mass flow (q) = s x px x ([x]c [x]if) Px = dx/a = permeability coefficient a = wall thickness; d = diffusion coefficient. Filtration related to hydrostatic and osmotic pressure imbalances. 2 4 l filtered per day by lymph. Jv = lp [(pc pif) ( c if)] = reflection coefficient to proteins ( = 1 (no passage)) Lp is index of ability to conduct water. Discontinuous capillaries show highest lp and lowest . Continuous capillaries show lowest lp and highest (brain is extreme example) Ingestion of lipid meal: increased lp and decreases . Inflammatory rx: increase lp and decrease edema. 35 mm hg to 15 mm hg along length (filter to absorb) Low in pulmonary arteries thus minimizing filtration to alveoli. Varies with time sometimes favoring filtration, at other times favoring absorption.

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