MIP 315A Lecture Notes - Ulcerative Colitis, Coeliac Disease, Pepsin
Document Summary
Know the basic physiology and anatomy of the g. i. system. Understand the pathogenesis of crohn"s disease and ulcerative colitis. Doesn"t have as many layers as the stomach. Stores food while it is being worked with ph usually between 2 and 3. Absorption proteins, peptides, amino acids, fats, triglycerides, nucleic acids . Goes to liver and gets detoxified through portal system (circulation) Lots of villi in interior increase of surface area. If acid eats through esophagus, contents may empty into thoracic cavity. Aspirin and other nonsteroidal anti-inflammatory drugs cause gastritis. Prostogladin causes pain and regulates mucus production in stomach. Pernicious anemia: a form of anemia that occurs when the stomach lacks a naturally occurring substance. Hernias (something moves into a space where it"s not normally found). Section of stomach moves up through hiatus into pleural cavity. If it hits a blood vessel bleeding ulcer. Two major types: crohn"s disease and ulcerative colitis. American jews of european descent are more susceptible.