ANSC 2120 Lecture Notes - Lecture 34: Phosphocreatine, Creatine Kinase, American Quarter Horse

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Contracting muscle has unique ability to perform external mechanical work. Muscular contraction requires atp as its immediate energy source. Muscle stores of atp can support only a few contractions so. Atp must be rapidly and continuously regenerated during muscle contraction. During heavy exercise, atp requirements of muscle may be increased 40-50 times resting requirements: untrained exercise uses more atp than trained. Phase i: short-term, anaerobic of exercise (short and long term) Creatine phosphate + adp creatine + atp (creatine kinase is activator) Forms lactic acid and makes meat tough. Rapid generation of atp from these sources can occur because of their location (stored in muscle) and because of their metabolism does not require o2. Phase ii: longer term generation of atp by oxidation of glucose and fatty acids. Lecture 34: working animal: glucose sources are. Muscle glycogen (early phase ii and also phase i) Blood glucose (most important with increasing duration) Triacylglycerols = best fuel source in the body.

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