BIOMG 1350 Lecture Notes - Lecture 4: Arginine, Hydrolysis, Lysine

• School: Cornell University
• Department: Molecular Biology and Genetics
• Course: BIOMG 1350
• Professor: Discussion

Document Summary

Proteins perform functions in the cell because they have the ability to bind to other proteins or chemicals in the cell. Ligands: anything that binds to the protein. Binding of the ligands are very specific. Binding dependent on noncovalent bonds (hydrogen, van der waals, etc) Needs to have many bonds because nc bonds are generally weak. Folds: binding sites form when aa side chains fold together and form a pocket for the ligand. Side chains form a surface for binding to the ligands. Active site: pocket that has the right aa side chains for the substrate. Enzymes increases the rate of chemical reactions (reduces the energy needed) Enzymes are not changed by the reaction, can be recycled. Enzymes catalyze reactions by lowering the activations energy barrier. Enzymes can encourage a reaction in several ways. Binds to 2 substrate molecules and orients them precisely to encourage reaction to occur between the 2 substrates.