BIOL 031 Lecture Notes - Lecture 2: Peptide Hormone, Golgi Apparatus, Peptide
17 May 2020
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Tyrosine derived: e. g. epinephrine, not lipid soluble, like polypeptide (see polypeptide) 1. mrna on ribosomes bind aa into a peptide chain called preprohormone. The chain is directed into er lumen by signal sequence of aa. Enzymes in er chop off signal sequence, creating inactive prohormone. The prohormone passes from the er through the golgi complex. Permissiveness: one hormone enhances cellular response to another hormone. Synergism: the combined effect of multiple hormones exceeds the sum of their individual effects. Antagonism: one hormone decreases the cellular response to another hormone. Amplitude of graded potential can vary substantially (can go up and down) Graded potentials decay from a point of origin. Speed of action potential in neuron influenced by. Diameter of axon: larger axons are faster. Myelin increases insulation and resistance to current leak, allows graded potential to get to another node effectively. An input signal with relatively low strength may still trigger an action potential if.
