BIOL 031 Lecture Notes - Lecture 29: Carbonic Anhydrase, Pulmonary Edema, Partial Pressure

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Resting cell po2 = 40 mm hg. Working cell po2 = 20 mm hg. This plots the partial pressure of oxygen versus the percent saturation of hemoglobin. As the blood flows from the alveoli to the tissues the percent of oxygen saturation of hemoglobin decreases. This is represented by moving left on the red curve, because the partial pressure of oxygen decreases when the blood flows from the alveoli to the tissues. The partial pressure would be lower (about 20 mm hg), more oxygen would be delivered and the percent saturation of hemoglobin would be even lower. Each plot is of the partial pressure of oxygen versus the percent oxygen saturation, as shown previously. Each of the changes shifts the curve that represents this relationship. As a result there are families of curves as the ph, temperature, or partial pressure of carbon dioxide change. These three changes occur in active tissues: Bohr effect: decreasing ph decreases o2 binding.

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