BIOL 031 Lecture Notes - Lecture 14: Plasma Osmolality, Carbonic Anhydrase, Electrochemical Gradient

• School: College of The Sequoias
• Department: Biology (BIOL)
• Course: BIOL 031
• Professor: carey

Document Summary

Ivf & diuretics: describe ivf what they contain and the rationale behind their use, ivf = intravenous fluids, things you should know: Serum osmolality = 2*[na] + [bun]/2. 8 + [glucose] /18: normal serum concentration (mmol/l) na=140, k=4, cl=100, normal osmolality of serum ~ 285-295, body water = 50-60% of body weight. Extracellular water = total body water: = plasma = extravascular, ivf goes into intravascular space. Also treat hypovolemic symptoms before hyperosmotic symptoms: types of ivf, mechanisms of action of each of the diuretic classes, proximal tubule diuretics. Inhibits carbonic anhydrase decrease intracellular [h+] and [hco3- ] less activity from na+/h+ antiporter and less activity from. Na+/hco3sodium symporter less na and bicarbonate reabsorption and less h+ secretion (acidosis). More [na] and [hco3] in urine: not a very powerful diuretic because more distal part of nephron can make up for the lack of na reabsorption, loop diuretics thick ascending loop of henle.